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BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy
Disruption of the complex of BECN1 with BCL2 or BCL2L1/BCL-X(L) is an essential switch that turns on cellular autophagy in response to environmental stress or treatment with BH3 peptidomimetics. Recently, it has been proposed that BCL2 and BCL2L1/BCL-X(L) may inhibit autophagy indirectly through a m...
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| Udgivet i: | Autophagy |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502763/ https://ncbi.nlm.nih.gov/pubmed/25715028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1017191 |
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