BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy

Disruption of the complex of BECN1 with BCL2 or BCL2L1/BCL-X(L) is an essential switch that turns on cellular autophagy in response to environmental stress or treatment with BH3 peptidomimetics. Recently, it has been proposed that BCL2 and BCL2L1/BCL-X(L) may inhibit autophagy indirectly through a m...

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Bibliografische gegevens
Gepubliceerd in:Autophagy
Hoofdauteurs: Pedro, Jose Manuel Bravo-San, Wei, Yongjie, Sica, Valentina, Maiuri, Maria Chiara, Zou, Zhongju, Kroemer, Guido, Levine, Beth
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2015
Onderwerpen:
Basic Brief Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502763/
https://ncbi.nlm.nih.gov/pubmed/25715028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1017191
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