A carregar...
TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control
The 18-kDa TSPO (translocator protein) localizes on the outer mitochondrial membrane (OMM) and participates in cholesterol transport. Here, we report that TSPO inhibits mitochondrial autophagy downstream of the PINK1-PARK2 pathway, preventing essential ubiquitination of proteins. TSPO abolishes mito...
Na minha lista:
| Publicado no: | Autophagy |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502750/ https://ncbi.nlm.nih.gov/pubmed/25470454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15548627.2014.991665 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|