HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease.

The most frequent DNA adduct made by the anticancer drug cisplatin, the 1,2-intrastrand d(GpG) cross-link, as well as the minor 1,3-intrastrand d(GpTpG) adduct, were both repaired by an in vitro human excision repair system. Fragments of 27-29 nt containing the platinum damage were excised. The high...

全面介紹

書目詳細資料

發表在:	Proc Natl Acad Sci U S A
Principais autores:	Huang, J C, Zamble, D B, Reardon, J T, Lippard, S J, Sancar, A
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1994
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45026/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937961/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.22.10394
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!