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The DNA-dependent protein kinase: a multifunctional protein kinase with roles in DNA double strand break repair and mitosis

The DNA-dependent protein kinase (DNA-PK) is a serine/threonine protein kinase composed of a large catalytic subunit (DNA-PKcs) and the Ku70/80 heterodimer. Over the past two decades, significant progress has been made in elucidating the role of DNA-PK in non-homologous end joining (NHEJ), the major...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Prog Biophys Mol Biol
Egile Nagusiak: Jette, Nicholas, Lees-Miller, Susan P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502593/
https://ncbi.nlm.nih.gov/pubmed/25550082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2014.12.003
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