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Conformational isomerism and the diversity of antibodies.

The fact that one cell encodes a single antibody sequence does not necessarily mean that the resulting antibody folds into a single structure, although this is a common assumption. Here we challenge this view and suggest that many antibodies do not have a single conformation at the combining site. T...

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Bibliografiske detaljer
Main Authors: Foote, J, Milstein, C
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC45021/
https://ncbi.nlm.nih.gov/pubmed/7937957
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