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Conformational Correction Mechanisms Aiding Antigen Recognition by a Humanized Antibody

The crystal structure of the complex between hen egg lysozyme and the Fv fragment of a humanized antilysozyme antibody was determined to 2.7-Å resolution. The structure of the antigen combining site in the complex is nearly identical to that of the complexed form of the parent mouse antibody, D1.3....

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Detalhes bibliográficos
Main Authors: Holmes, Margaret A., Buss, Timothy N., Foote, Jefferson
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212146/
https://ncbi.nlm.nih.gov/pubmed/9463398
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