Enacyloxin IIa, an inhibitor of protein biosynthesis that acts on elongation factor Tu and the ribosome.

This work analyzes the action of enacyloxin Ila, an inhibitor of bacterial protein biosynthesis. Enacyloxin IIa [IC50 on poly(Phe) synthesis approximately 70 nM] is shown to affect the interaction between elongation factor (EF) Tu and GTP or GDP; in particular, the dissociation of EF-Tu-GTP is stron...

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Detalhes bibliográficos
Main Authors: Cetin, R, Krab, I M, Anborgh, P H, Cool, R H, Watanabe, T, Sugiyama, T, Izaki, K, Parmeggiani, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC450193/
https://ncbi.nlm.nih.gov/pubmed/8665868
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