GTPase activation of elongation factor EF-Tu by the ribosome during decoding

We have used single-particle reconstruction in cryo-electron microscopy to determine a structure of the Thermus thermophilus ribosome in which the ternary complex of elongation factor Tu (EF-Tu), tRNA and guanine nucleotide has been trapped on the ribosome using the antibiotic kirromycin. This repre...

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Detalhes bibliográficos
Main Authors: Schuette, Jan-Christian, Murphy, Frank V, Kelley, Ann C, Weir, John R, Giesebrecht, Jan, Connell, Sean R, Loerke, Justus, Mielke, Thorsten, Zhang, Wei, Penczek, Pawel A, Ramakrishnan, V, Spahn, Christian M T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666022/
https://ncbi.nlm.nih.gov/pubmed/19229291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.26
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