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Mechanical Load Increases in Bone Formation via a Sclerostin-Independent Pathway

Sclerostin, encoded by the Sost gene, is an important negative regulator of bone formation that has been proposed to have a key role in regulating the response to mechanical loading. To investigate the effect of long-term Sclerostin deficiency on mechanotransduction in bone, we performed experiments...

詳細記述

保存先:
書誌詳細
出版年:J Bone Miner Res
主要な著者: Morse, Alyson, McDonald, Michelle Maree, Kelly, Natalie H, Melville, Katherine M, Schindeler, Aaron, Kramer, Ina, Kneissel, Michaela, van der Meulen, Marjolein CH, Little, David Graham
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501925/
https://ncbi.nlm.nih.gov/pubmed/24821585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2278
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