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Mechanical Load Increases in Bone Formation via a Sclerostin-Independent Pathway
Sclerostin, encoded by the Sost gene, is an important negative regulator of bone formation that has been proposed to have a key role in regulating the response to mechanical loading. To investigate the effect of long-term Sclerostin deficiency on mechanotransduction in bone, we performed experiments...
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| Publicado no: | J Bone Miner Res |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4501925/ https://ncbi.nlm.nih.gov/pubmed/24821585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2278 |
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