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Mechanisms of Activation of Nucleus Accumbens Neurons by Cocaine via Sigma-1 Receptor - Inositol 1,4,5-Trisphosphate - Transient Receptor Potential Canonical Channel Pathways
Cocaine promotes addictive behavior primarily by blocking the dopamine transporter, thus increasing dopamine transmission in the nucleus accumbens (nAcc); however, additional mechanisms are continually emerging. Sigma-1 receptors (σ(1)Rs) are known targets for cocaine, yet the mechanisms underlying...
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| Foilsithe in: | Cell Calcium |
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| Main Authors: | , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2015
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4501893/ https://ncbi.nlm.nih.gov/pubmed/26077147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2015.05.001 |
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