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Genistein Increases Estrogen Receptor Beta Expression in Prostate Cancer via Reducing its Promoter Methylation

Genistein has protective effects against prostate cancer (PCa) but whether this protection involves an estrogen receptor (ER) β dependent mechanism has yet to be elucidated. ER-β has a tumor suppressor role in PCa and its levels decline with cancer progression which was linked to ER-β promoter hyper...

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Detalhes bibliográficos
Publicado no:J Steroid Biochem Mol Biol
Main Authors: Mahmoud, Abeer M., Al-alem, Umaima, Ali, Mohamed M., Bosland, Maarten C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501888/
https://ncbi.nlm.nih.gov/pubmed/25931004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2015.04.018
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