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Differential Effects of Genistein on Prostate Cancer Cells Depend on Mutational Status of the Androgen Receptor
Blocking the androgen receptor (AR) activity is the main goal of therapies for advanced prostate cancer (PCa). However, relapse with a more aggressive, hormone refractory PCa arises, which harbors restored AR activity. One mechanism of such reactivation occurs through acquisition of AR mutations tha...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805529/ https://ncbi.nlm.nih.gov/pubmed/24167630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078479 |
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