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Differential Effects of Genistein on Prostate Cancer Cells Depend on Mutational Status of the Androgen Receptor

Blocking the androgen receptor (AR) activity is the main goal of therapies for advanced prostate cancer (PCa). However, relapse with a more aggressive, hormone refractory PCa arises, which harbors restored AR activity. One mechanism of such reactivation occurs through acquisition of AR mutations tha...

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Bibliografski detalji
Glavni autori: Mahmoud, Abeer M., Zhu, Tian, Parray, Aijaz, Siddique, Hifzur R., Yang, Wancai, Saleem, Mohammad, Bosland, Maarten C.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805529/
https://ncbi.nlm.nih.gov/pubmed/24167630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078479
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