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A cysteine residue in the third membrane-spanning segment of the human D2 dopamine receptor is exposed in the binding-site crevice.

The binding site in G-protein-linked neurotransmitter receptors is formed among their membrane-spanning segments. Because the binding site is in the plane of the bilayer and is accessible to charged, water-soluble agonists, it must lie in a crevice open to the extracellular, aqueous medium. Informat...

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Detalles Bibliográficos
Main Authors: Javitch, J A, Li, X, Kaback, J, Karlin, A
Formato: Artigo
Idioma:Inglês
Publicado: 1994
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC45018/
https://ncbi.nlm.nih.gov/pubmed/7937955
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