Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease

Inflammation defines the progression of ALD from reversible to advanced stages. Translocation of bacterial LPS to the liver from the gut is necessary for alcohol-induced liver inflammation. However, it is not known whether endogenous, metabolic danger signals are required for inflammation in ALD. Ur...

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Detalles Bibliográficos
Publicado en:J Leukoc Biol
Main Authors: Petrasek, Jan, Iracheta-Vellve, Arvin, Saha, Banishree, Satishchandran, Abhishek, Kodys, Karen, Fitzgerald, Katherine A., Kurt-Jones, Evelyn A., Szabo, Gyongyi
Formato: Artigo
Idioma:Inglês
Publicado: Society for Leukocyte Biology 2015
Assuntos:
Inflammation, Extracellular Mediators, & Effector Molecules
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501673/
https://ncbi.nlm.nih.gov/pubmed/25934928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3AB1214-590R
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