Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease

Inflammation defines the progression of ALD from reversible to advanced stages. Translocation of bacterial LPS to the liver from the gut is necessary for alcohol-induced liver inflammation. However, it is not known whether endogenous, metabolic danger signals are required for inflammation in ALD. Ur...

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Veröffentlicht in:J Leukoc Biol
Hauptverfasser: Petrasek, Jan, Iracheta-Vellve, Arvin, Saha, Banishree, Satishchandran, Abhishek, Kodys, Karen, Fitzgerald, Katherine A., Kurt-Jones, Evelyn A., Szabo, Gyongyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Leukocyte Biology 2015
Schlagworte:
Inflammation, Extracellular Mediators, & Effector Molecules
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501673/
https://ncbi.nlm.nih.gov/pubmed/25934928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3AB1214-590R
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