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A Drosophila ribosomal protein contains 8-oxoguanine and abasic site DNA repair activities.

Ionizing radiation and normal cellular respiration form reactive oxygen species that damage DNA and contribute to a variety of human disorders including tumor promotion and carcinogenesis. A major product of free radical DNA damage is the formation of 8-oxoguanine, which is a highly mutagenic base m...

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Bibliographic Details
Main Authors: Yacoub, A, Augeri, L, Kelley, M R, Doetsch, P W, Deutsch, W A
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC450156/
https://ncbi.nlm.nih.gov/pubmed/8641296
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