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An in vitro iron superoxide dismutase inhibitor decreases the parasitemia levels of Trypanosoma cruzi in BALB/c mouse model during acute phase

In order to identify new compounds to treat Chagas disease during the acute phase with higher activity and lower toxicity than the reference drug benznidazole (Bz), two hydroxyphthalazine derivative compounds were prepared and their trypanocidal effects against Trypanosoma cruzi were evaluated by li...

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Bibliografische gegevens
Gepubliceerd in:Int J Parasitol Drugs Drug Resist
Hoofdauteurs: Olmo, Francisco, Urbanová, Kristína, Rosales, Maria Jose, Martín-Escolano, Ruben, Sánchez-Moreno, Manuel, Marín, Clotilde
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501536/
https://ncbi.nlm.nih.gov/pubmed/26236582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2015.05.002
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