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An in vitro iron superoxide dismutase inhibitor decreases the parasitemia levels of Trypanosoma cruzi in BALB/c mouse model during acute phase

In order to identify new compounds to treat Chagas disease during the acute phase with higher activity and lower toxicity than the reference drug benznidazole (Bz), two hydroxyphthalazine derivative compounds were prepared and their trypanocidal effects against Trypanosoma cruzi were evaluated by li...

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Detaylı Bibliyografya
Yayımlandı:Int J Parasitol Drugs Drug Resist
Asıl Yazarlar: Olmo, Francisco, Urbanová, Kristína, Rosales, Maria Jose, Martín-Escolano, Ruben, Sánchez-Moreno, Manuel, Marín, Clotilde
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501536/
https://ncbi.nlm.nih.gov/pubmed/26236582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2015.05.002
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