Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase overexpression

Trypanosoma cruzi undergo PCD (programmed cell death) under appropriate stimuli, the mechanisms of which remain to be established. In the present study, we show that stimulation of PCD in T. cruzi epimastigotes by FHS (fresh human serum) results in rapid (<1 h) externalization of phosphatidylseri...

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Bibliografische gegevens
Hoofdauteurs: Piacenza, Lucía, Irigoín, Florencia, Alvarez, María Noel, Peluffo, Gonzalo, Taylor, Martin C., Kelly, John M., Wilkinson, Shane R., Radi, Rafael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Portland Press Ltd. 2007
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874241/
https://ncbi.nlm.nih.gov/pubmed/17168856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061281
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