Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase overexpression

Trypanosoma cruzi undergo PCD (programmed cell death) under appropriate stimuli, the mechanisms of which remain to be established. In the present study, we show that stimulation of PCD in T. cruzi epimastigotes by FHS (fresh human serum) results in rapid (<1 h) externalization of phosphatidylseri...

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Detalhes bibliográficos
Main Authors: Piacenza, Lucía, Irigoín, Florencia, Alvarez, María Noel, Peluffo, Gonzalo, Taylor, Martin C., Kelly, John M., Wilkinson, Shane R., Radi, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874241/
https://ncbi.nlm.nih.gov/pubmed/17168856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061281
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