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An in vitro iron superoxide dismutase inhibitor decreases the parasitemia levels of Trypanosoma cruzi in BALB/c mouse model during acute phase

In order to identify new compounds to treat Chagas disease during the acute phase with higher activity and lower toxicity than the reference drug benznidazole (Bz), two hydroxyphthalazine derivative compounds were prepared and their trypanocidal effects against Trypanosoma cruzi were evaluated by li...

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Podrobná bibliografie
Vydáno v:Int J Parasitol Drugs Drug Resist
Hlavní autoři: Olmo, Francisco, Urbanová, Kristína, Rosales, Maria Jose, Martín-Escolano, Ruben, Sánchez-Moreno, Manuel, Marín, Clotilde
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501536/
https://ncbi.nlm.nih.gov/pubmed/26236582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2015.05.002
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