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An in vitro iron superoxide dismutase inhibitor decreases the parasitemia levels of Trypanosoma cruzi in BALB/c mouse model during acute phase

In order to identify new compounds to treat Chagas disease during the acute phase with higher activity and lower toxicity than the reference drug benznidazole (Bz), two hydroxyphthalazine derivative compounds were prepared and their trypanocidal effects against Trypanosoma cruzi were evaluated by li...

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書目詳細資料
發表在:Int J Parasitol Drugs Drug Resist
Main Authors: Olmo, Francisco, Urbanová, Kristína, Rosales, Maria Jose, Martín-Escolano, Ruben, Sánchez-Moreno, Manuel, Marín, Clotilde
格式: Artigo
語言:Inglês
出版: Elsevier 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501536/
https://ncbi.nlm.nih.gov/pubmed/26236582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2015.05.002
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