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Mycalolide B dissociates dynactin and abolishes retrograde axonal transport of dense-core vesicles

Axonal transport is critical for maintaining synaptic transmission. Of interest, anterograde and retrograde axonal transport appear to be interdependent, as perturbing one directional motor often impairs movement in the opposite direction. Here live imaging of Drosophila and hippocampal neuron dense...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Cavolo, Samantha L., Zhou, Chaoming, Ketcham, Stephanie A., Suzuki, Matthew M., Ukalovic, Kresimir, Silverman, Michael A., Schroer, Trina A., Levitan, Edwin S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501363/
https://ncbi.nlm.nih.gov/pubmed/26023088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-11-1564
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