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Ordered Recruitment of Dynactin to the Microtubule Plus-End is Required for Efficient Initiation of Retrograde Axonal Transport

Long-range retrograde axonal transport in neurons is driven exclusively by the microtubule motor cytoplasmic dynein. The efficient initiation of dynein-mediated transport from the distal axon is critical for normal neuronal function, and neurodegenerative disease-associated mutations have been shown...

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Detalhes bibliográficos
Main Authors: Moughamian, Armen J., Osborn, Gregory E., Lazarus, Jacob E., Maday, Sandra, Holzbaur, Erika L.F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735891/
https://ncbi.nlm.nih.gov/pubmed/23926272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0935-13.2013
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