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HIF hydroxylase pathways in cardiovascular physiology and medicine

Hypoxia inducible factors (HIFs) are alpha/beta heterodimeric transcription factors that direct multiple cellular and systemic responses in response to changes in oxygen availability. The oxygen sensitive signal is generated by a series of iron and 2-oxoglutarate dependent dioxygenases that catalyse...

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Détails bibliographiques
Publié dans:Circ Res
Auteurs principaux: Bishop, Tammie, Ratcliffe, Peter J.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501273/
https://ncbi.nlm.nih.gov/pubmed/26089364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.305109
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