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Altered protease and antiprotease balance during a COPD exacerbation contributes to mucus obstruction
BACKGROUND: Proteases have been shown to degrade airway mucin proteins and to damage the epithelium impairing mucociliary clearance. There are increased proteases in the COPD airway but changes in protease-antiprotease balance and mucin degradation have not been investigated during the course of a C...
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| Pubblicato in: | Respir Res |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4501272/ https://ncbi.nlm.nih.gov/pubmed/26169056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0247-x |
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