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Altered protease and antiprotease balance during a COPD exacerbation contributes to mucus obstruction
BACKGROUND: Proteases have been shown to degrade airway mucin proteins and to damage the epithelium impairing mucociliary clearance. There are increased proteases in the COPD airway but changes in protease-antiprotease balance and mucin degradation have not been investigated during the course of a C...
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| Publicat a: | Respir Res |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4501272/ https://ncbi.nlm.nih.gov/pubmed/26169056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0247-x |
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