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Serine Proteases Degrade Airway Mucins in Cystic Fibrosis

Airway mucins are the major molecular constituents of mucus. Mucus forms the first barrier to invading organisms in the airways and is an important defense mechanism of the lung. We confirm that mucin concentrations are significantly decreased in airway secretions of subjects with cystic fibrosis (C...

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Auteurs principaux: Henke, Markus O., John, Gerrit, Rheineck, Christina, Chillappagari, Shashi, Naehrlich, Lutz, Rubin, Bruce K.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147599/
https://ncbi.nlm.nih.gov/pubmed/21646446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01252-10
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