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TLR-4–Mediated Innate Immunity Is Reduced in Cystic Fibrosis Airway Cells

Airway epithelial cells contribute to the inflammatory response of the lung, and their innate immune response is primarily mediated via Toll-like receptor (TLR) signaling. Cystic fibrosis (CF) airways are chronically infected with Pseudomonas aeruginosa, suggesting a modified immune response in CF....

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Bibliographic Details
Published in:Am J Respir Cell Mol Biol
Main Authors: John, Gerrit, Yildirim, Ali Ö., Rubin, Bruce K., Gruenert, Dieter C., Henke, Markus O.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459530/
https://ncbi.nlm.nih.gov/pubmed/19502387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0408OC
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