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Intracellular Crotonyl-CoA Stimulates Transcription Through p300-Catalyzed Histone Crotonylation

Acetylation of histones at DNA regulatory elements plays a critical role in transcriptional activation. Histones are also modified by other acyl moieties, including crotonyl, yet the mechanisms that govern acetylation versus crotonylation and the functional consequences of this “choice” remain uncle...

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Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Sabari, Benjamin R., Tang, Zhanyun, Huang, He, Yong-Gonzalez, Vladimir, Molina, Henrik, Kong, Ha Eun, Dai, Lunzhi, Shimada, Miho, Cross, Justin R., Zhao, Yingming, Roeder, Robert G., Allis, C. David
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501262/
https://ncbi.nlm.nih.gov/pubmed/25818647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.02.029
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