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Intracellular Crotonyl-CoA Stimulates Transcription Through p300-Catalyzed Histone Crotonylation
Acetylation of histones at DNA regulatory elements plays a critical role in transcriptional activation. Histones are also modified by other acyl moieties, including crotonyl, yet the mechanisms that govern acetylation versus crotonylation and the functional consequences of this “choice” remain uncle...
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| Udgivet i: | Mol Cell |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4501262/ https://ncbi.nlm.nih.gov/pubmed/25818647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.02.029 |
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