Intracellular Crotonyl-CoA Stimulates Transcription Through p300-Catalyzed Histone Crotonylation

Acetylation of histones at DNA regulatory elements plays a critical role in transcriptional activation. Histones are also modified by other acyl moieties, including crotonyl, yet the mechanisms that govern acetylation versus crotonylation and the functional consequences of this “choice” remain uncle...

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Bibliografiska uppgifter
I publikationen:Mol Cell
Huvudupphovsmän: Sabari, Benjamin R., Tang, Zhanyun, Huang, He, Yong-Gonzalez, Vladimir, Molina, Henrik, Kong, Ha Eun, Dai, Lunzhi, Shimada, Miho, Cross, Justin R., Zhao, Yingming, Roeder, Robert G., Allis, C. David
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501262/
https://ncbi.nlm.nih.gov/pubmed/25818647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.02.029
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