Intracellular Crotonyl-CoA Stimulates Transcription Through p300-Catalyzed Histone Crotonylation

Acetylation of histones at DNA regulatory elements plays a critical role in transcriptional activation. Histones are also modified by other acyl moieties, including crotonyl, yet the mechanisms that govern acetylation versus crotonylation and the functional consequences of this “choice” remain uncle...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Sabari, Benjamin R., Tang, Zhanyun, Huang, He, Yong-Gonzalez, Vladimir, Molina, Henrik, Kong, Ha Eun, Dai, Lunzhi, Shimada, Miho, Cross, Justin R., Zhao, Yingming, Roeder, Robert G., Allis, C. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501262/
https://ncbi.nlm.nih.gov/pubmed/25818647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.02.029
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