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Glanzmann’s thrombasthenia: pathogenesis, diagnosis, and current and emerging treatment options
Glanzmann’s thrombasthenia (GT) is a genetic platelet surface receptor disorder of GPIIb/IIIa (ITG αIIbβ3), either qualitative or quantitative, which results in faulty platelet aggregation and diminished clot retraction. Spontaneous mucocutaneous bleeding is common and can lead to fatal bleeding epi...
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| Vydáno v: | J Blood Med |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Dove Medical Press
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4501245/ https://ncbi.nlm.nih.gov/pubmed/26185478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JBM.S71319 |
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