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Glanzmann’s thrombasthenia: pathogenesis, diagnosis, and current and emerging treatment options
Glanzmann’s thrombasthenia (GT) is a genetic platelet surface receptor disorder of GPIIb/IIIa (ITG αIIbβ3), either qualitative or quantitative, which results in faulty platelet aggregation and diminished clot retraction. Spontaneous mucocutaneous bleeding is common and can lead to fatal bleeding epi...
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| 出版年: | J Blood Med |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove Medical Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4501245/ https://ncbi.nlm.nih.gov/pubmed/26185478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JBM.S71319 |
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