p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction.

The tumour suppressor p53 prevents tumour formation after DNA damage by halting cell cycle progression to allow DNA repair or by inducing apoptotic cell death. Loss of wild-type p53 function renders cells resistant to DNA damage-induced cell cycle arrest and ultimately leads to genomic instabilities...

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Bibliografske podrobnosti
Main Authors: Stürzbecher, H W, Donzelmann, B, Henning, W, Knippschild, U, Buchhop, S
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC450118/
https://ncbi.nlm.nih.gov/pubmed/8617246
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