p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction.

The tumour suppressor p53 prevents tumour formation after DNA damage by halting cell cycle progression to allow DNA repair or by inducing apoptotic cell death. Loss of wild-type p53 function renders cells resistant to DNA damage-induced cell cycle arrest and ultimately leads to genomic instabilities...

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Bibliografische Detailangaben

Veröffentlicht in:	EMBO J
Hauptverfasser:	Stürzbecher, H W, Donzelmann, B, Henning, W, Knippschild, U, Buchhop, S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8617246/
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