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An integrative pan-cancer-wide analysis of epigenetic enzymes reveals universal patterns of epigenomic deregulation in cancer

BACKGROUND: One of the most important recent findings in cancer genomics is the identification of novel driver mutations which often target genes that regulate genome-wide chromatin and DNA methylation marks. Little is known, however, as to whether these genes exhibit patterns of epigenomic deregula...

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Vydáno v:Genome Biol
Hlavní autoři: Yang, Zhen, Jones, Allison, Widschwendter, Martin, Teschendorff, Andrew E.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501092/
https://ncbi.nlm.nih.gov/pubmed/26169266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0699-9
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