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Epigenetic and genetic deregulation in cancer target distinct signaling pathway domains

Cancer is characterized by both genetic and epigenetic alterations. While cancer driver mutations and copy-number alterations have been studied at a systems-level, relatively little is known about the systems-level patterns exhibited by their epigenetic counterparts. Here we perform a pan-cancer wid...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Gao, Yang, Teschendorff, Andrew E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314760/
https://ncbi.nlm.nih.gov/pubmed/27899617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1100
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