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Fast imputation using medium or low-coverage sequence data

BACKGROUND: Accurate genotype imputation can greatly reduce costs and increase benefits by combining whole-genome sequence data of varying read depth and array genotypes of varying densities. For large populations, an efficient strategy chooses the two haplotypes most likely to form each genotype an...

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Bibliografske podrobnosti
izdano v:BMC Genet
Main Authors: VanRaden, Paul M., Sun, Chuanyu, O’Connell, Jeffrey R.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501077/
https://ncbi.nlm.nih.gov/pubmed/26168789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-015-0243-7
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