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Efficient Imputation of Missing Markers in Low-Coverage Genotyping-by-Sequencing Data from Multiparental Crosses

We consider genomic imputation for low-coverage genotyping-by-sequencing data with high levels of missing data. We compensate for this loss of information by utilizing family relationships in multiparental experimental crosses. This nearly quadruples the number of usable markers when applied to a la...

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Detalhes bibliográficos
Main Authors: Huang, B. Emma, Raghavan, Chitra, Mauleon, Ramil, Broman, Karl W., Leung, Hei
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012496/
https://ncbi.nlm.nih.gov/pubmed/24583583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.158014
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