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Efficient Imputation of Missing Markers in Low-Coverage Genotyping-by-Sequencing Data from Multiparental Crosses

We consider genomic imputation for low-coverage genotyping-by-sequencing data with high levels of missing data. We compensate for this loss of information by utilizing family relationships in multiparental experimental crosses. This nearly quadruples the number of usable markers when applied to a la...

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Bibliografski detalji
Glavni autori: Huang, B. Emma, Raghavan, Chitra, Mauleon, Ramil, Broman, Karl W., Leung, Hei
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012496/
https://ncbi.nlm.nih.gov/pubmed/24583583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.158014
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