Early life lead exposure causes gender-specific changes in the DNA methylation profile of DNA extracted from dried blood spots

AIMS: In this paper, we tested the hypothesis that early life lead (Pb) exposure associated DNA methylation (5mC) changes are dependent on the sex of the child and can serve as biomarkers for Pb exposure. METHODS: In this pilot study, we measured the 5mC profiles of DNA extracted from dried blood sp...

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Veröffentlicht in:Epigenomics
Hauptverfasser: Sen, Arko, Heredia, Nicole, Senut, Marie-Claude, Hess, Matthew, Land, Susan, Qu, Wen, Hollacher, Kurt, Dereski, Mary O, Ruden, Douglas M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501025/
https://ncbi.nlm.nih.gov/pubmed/26077427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.15.2
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