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Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications

The receptor for advanced glycation endproducts (RAGE) was first described as a signal transduction receptor for advanced glycation endproducts (AGEs), the products of nonenzymatic glycation and oxidation of proteins and lipids that accumulate in diabetes and in inflammatory foci. The discovery that...

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Bibliographic Details
Published in:Ann N Y Acad Sci
Main Authors: Ramasamy, Ravichandran, Yan, Shi Fang, Schmidt, Ann Marie
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501013/
https://ncbi.nlm.nih.gov/pubmed/22211895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2011.06320.x
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