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The RAGE Axis: a Fundamental Mechanism Signaling Danger to the Vulnerable Vasculature

The immunoglobulin superfamily molecule RAGE transduces the effects of multiple ligands, including advanced glycation endproducts (AGEs), advanced oxidation protein products (AOPPs), S100/calgranulins, high mobility group box-1, amyloid-β peptide and β-sheet fibrils. In diabetes, hyperglycemia likel...

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Detalhes bibliográficos
Main Authors: Yan, Shi Fang, Ramasamy, Ravichandran, Schmidt, Ann Marie
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862596/
https://ncbi.nlm.nih.gov/pubmed/20299674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.212217
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