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Tempering the Wrath of RAGE: An Emerging Therapeutic Strategy Against Diabetic Complications, Neurodegeneration and Inflammation

The multi-ligand receptor RAGE (Receptor for Advanced Glycation Endproducts) is emerging as a central mediator in the immune/inflammatory response. Epidemiological evidence accruing in the human suggests upregulation of RAGE’s ligands (AGEs, S100/calgranulins, HMGB1 and amyloid β-peptide and β-sheet...

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Detalhes bibliográficos
Main Authors: Yan, Shi Fang, Yan, Shi Du, Ramasamy, Ravichandran, Schmidt, Ann Marie
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932796/
https://ncbi.nlm.nih.gov/pubmed/19322705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07853890902806576
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