लोड हो रहा है...
Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies
The envelope spike of HIV-1 employs a ‘glycan shield’ to protect itself from antibody-mediated neutralization. Paradoxically, however, potent broadly neutralizing antibodies (bnAbs) have been isolated which target this shield. The unusually high glycan density on the gp120 subunit limits processing...
में बचाया:
| में प्रकाशित: | Nat Commun |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4500839/ https://ncbi.nlm.nih.gov/pubmed/26105115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8479 |
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