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Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect.
Physiological concentrations of urokinase plasminogen activator (uPA) stimulated a chemotactic response in human monocytic THP-1 through binding to the urokinase receptor (uPAR). The effect did not require the protease moiety of uPA, as stimulation was achieved also with the N-terminal fragment (ATF...
Guardat en:
| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450067/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8612581/ |
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