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A urokinase-sensitive region of the human urokinase receptor is responsible for its chemotactic activity.

The role of urokinase-type plasminogen activator (uPA) and its receptor (uPAR/CD87) in cell migration and invasion is well substantiated. Recently, uPA has been shown to be essential in cell migration, since uPA-/- mice are greatly impaired in inflammatory cell recruitment. We have shown previously...

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Bibliografiske detaljer
Main Authors: Fazioli, F, Resnati, M, Sidenius, N, Higashimoto, Y, Appella, E, Blasi, F
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170328/
https://ncbi.nlm.nih.gov/pubmed/9405357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.24.7279
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