Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation.

Interleukin-6 (IL-6) induces growth arrest and macrophage differentiation through its receptor in a murine myeloid leukaemic cell line, M1, although it is largely unknown how the IL-6 receptor generates these signals. By using chimeric receptors consisting of the extracellular domain of growth hormo...

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Pubblicato in:	EMBO J
Autori principali:	Yamanaka, Y, Nakajima, K, Fukada, T, Hibi, M, Hirano, T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450065/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8612579/
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