טוען...

Targeted disruption of the insulin receptor gene in the mouse results in neonatal lethality.

Targeted disruption of the insulin receptor gene (Insr) in the mouse was achieved using the homologous recombination approach. Insr+/- mice were normal as shown by glucose tolerance tests. Normal Insr-/- pups were born at expected rates, indicating that Insr can be dispensable for intrauterine devel...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:EMBO J
Main Authors: Joshi, R L, Lamothe, B, Cordonnier, N, Mesbah, K, Monthioux, E, Jami, J, Bucchini, D
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 1996
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450062/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8612577/
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