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Regulatory regions of rat insulin I gene necessary for expression in transgenic mice.
Ten transgenic mouse lines harboring the -346/-103 fragment of the rat insulin I enhancer linked to a heterologous promoter and a reporter gene (Eins-Ptk-CAT construct) were produced. Expression of the hybrid transgene was essentially observed in pancreas and to a lesser extent in brain. These resul...
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| Main Authors: | , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
1991
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC328791/ https://ncbi.nlm.nih.gov/pubmed/1923760 |
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