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Regulatory regions of rat insulin I gene necessary for expression in transgenic mice.

Ten transgenic mouse lines harboring the -346/-103 fragment of the rat insulin I enhancer linked to a heterologous promoter and a reporter gene (Eins-Ptk-CAT construct) were produced. Expression of the hybrid transgene was essentially observed in pancreas and to a lesser extent in brain. These resul...

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Библиографические подробности
Главные авторы: Dandoy-Dron, F, Monthioux, E, Jami, J, Bucchini, D
Формат: Artigo
Язык:Inglês
Опубликовано: 1991
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC328791/
https://ncbi.nlm.nih.gov/pubmed/1923760
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