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KCNQ1 channel modulation by KCNE proteins via the voltage-sensing domain
The gating of the KCNQ1 potassium channel is drastically regulated by auxiliary subunit KCNE proteins. KCNE1, for example, slows the activation kinetics of KCNQ1 by two orders of magnitude. Like other voltage-gated ion channels, the opening of KCNQ1 is regulated by the voltage-sensing domain (VSD; S...
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| Veröffentlicht in: | J Physiol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley & Sons, Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4500347/ https://ncbi.nlm.nih.gov/pubmed/25603957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.287672 |
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