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Advanced analyses of kinetic stabilities of iggs modified by mutations and glycosylation

The stability of Immunoglobulin G (IgG) affects production, storage and usability, especially in the clinic. The complex thermal and isothermal transitions of IgGs, especially their irreversibilities, pose a challenge to the proper determination of parameters describing their thermodynamic and kinet...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Sedlák, Erik, Schaefer, Jonas V, Marek, Jozef, Gimeson, Peter, Plückthun, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500310/
https://ncbi.nlm.nih.gov/pubmed/25966898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2691
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