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Cleavage of sterol regulatory element binding proteins (SREBPs) by CPP32 during apoptosis.
Cellular cholesterol homeostasis is controlled by sterol-regulated proteolysis of membrane-bound transcription factors called sterol-regulatory element binding proteins (SREBPs). CPP32, a cysteine protease, was shown previously to cleave SREBP-1 and SREBP-2 in vitro at an aspartic acid between the b...
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| 出版年: | EMBO J |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
1996
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC449996/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8605870/ |
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